<it>WRN </it>polymorphisms affect expression levels of plasminogen activator inhibitor type 1 in cultured fibroblasts

<p>Abstract</p> <p>Background</p> <p>Recessive mutations in <it>WRN </it>gene eliminate WRN protein function (helicase) and cause Werner syndrome. One of the most important clinical features of Werner syndrome patients are the premature onset and accelerated...

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Bibliographic Details
Main Authors: Oviedo-Rodríguez Vladimir, Castro Elena, Angel-Chávez Luis I
Format: Article
Language:English
Published: BMC 2008-02-01
Series:BMC Cardiovascular Disorders
Online Access:http://www.biomedcentral.com/1471-2261/8/5