<it>WRN </it>polymorphisms affect expression levels of plasminogen activator inhibitor type 1 in cultured fibroblasts
<p>Abstract</p> <p>Background</p> <p>Recessive mutations in <it>WRN </it>gene eliminate WRN protein function (helicase) and cause Werner syndrome. One of the most important clinical features of Werner syndrome patients are the premature onset and accelerated...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2008-02-01
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Series: | BMC Cardiovascular Disorders |
Online Access: | http://www.biomedcentral.com/1471-2261/8/5 |