Iron-sulphur cluster biogenesis factor LYRM4 is a novel prognostic biomarker associated with immune infiltrates in hepatocellular carcinoma

Iron-sulphur cluster biogenesis factor LYRM4 is a novel prognostic biomarker associated with immune infiltrates in hepatocellular carcinoma

Abstract Background LYRM4 is necessary to maintain the stability and activity of the human cysteine desulfurase complex NFS1-LYRM4-ACP. The existing experimental results indicate that cancer cells rely on the high expression of NFS1. However, the role of LYRM4 in liver hepatocellular carcinoma (LIHC...

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Bibliographic Details
Main Authors: Yilin Pang, Guoqiang Tan, Xunjun Yang, Yuanshan Lin, Yao Chen, Jinping Zhang, Ting Xie, Huaibin Zhou, Jun Fang, Qiongya Zhao, Xiaojun Ren, Jianghui Li, Jianxin Lyu, Zheng Wang
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Cancer Cell International
Subjects:
LYRM4
Hepatocellular carcinoma
Prognosis
Diagnostic biomarker
Functional network analysis
Online Access:https://doi.org/10.1186/s12935-021-02131-3

Internet

https://doi.org/10.1186/s12935-021-02131-3

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