Rapid insulinotropic action of low doses of bisphenol-A on mouse and human islets of Langerhans: role of estrogen receptor β.

Rapid insulinotropic action of low doses of bisphenol-A on mouse and human islets of Langerhans: role of estrogen receptor β.

Bisphenol-A (BPA) is a widespread endocrine-disrupting chemical (EDC) used as the base compound in the manufacture of polycarbonate plastics. It alters pancreatic β-cell function and can be considered a risk factor for type 2 diabetes in rodents. Here we used ERβ-/- mice to study whether ERβ is invo...

Full description

Bibliographic Details
Main Authors: Sergi Soriano, Paloma Alonso-Magdalena, Marta García-Arévalo, Anna Novials, Sarheed J Muhammed, Albert Salehi, Jan-Ake Gustafsson, Ivan Quesada, Angel Nadal
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22347437/?tool=EBI

Similar Items

Similar Items