Advances in Understanding the Roles of CD244 (SLAMF4) in Immune Regulation and Associated Diseases

Advances in Understanding the Roles of CD244 (SLAMF4) in Immune Regulation and Associated Diseases

Proteins in the signaling lymphocytic activating molecule (SLAM) family play crucial roles in regulating the immune system. CD244 (SLAMF4) is a protein in this family, and is also a member of the CD2 subset of the immunoglobulin (Ig) superfamily. CD244 is a cell surface protein expressed by NK cells...

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Bibliographic Details
Main Authors: Lin Sun, Xiaokun Gang, Zhuo Li, Xue Zhao, Tong Zhou, Siwen Zhang, Guixia Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Immunology
Subjects:
SLAMF4
disease models
autoimmune disease
immune cells
immune regulation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.648182/full

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