Structural and biochemical analyses of monoubiquitinated human histones H2B and H4

Monoubiquitination is a major histone post-translational modification. In humans, the histone H2B K120 and histone H4 K31 residues are monoubiquitinated and may form transcriptionally active chromatin. In this study, we reconstituted nucleosomes containing H2B monoubiquitinated at position 120 (H2Bu...

Full description

Bibliographic Details
Main Authors: Shinichi Machida, Satoshi Sekine, Yuuki Nishiyama, Naoki Horikoshi, Hitoshi Kurumizaka
Format: Article
Language:English
Published: The Royal Society 2016-01-01
Series:Open Biology
Subjects:
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.160090