Lipidomic Profiling of Ipsilateral Brain and Plasma after Celastrol Post-Treatment in Transient Middle Cerebral Artery Occlusion Mice Model

Lipidomic Profiling of Ipsilateral Brain and Plasma after Celastrol Post-Treatment in Transient Middle Cerebral Artery Occlusion Mice Model

Celastrol, a pentacyclic triterpene isolated from the traditional Chinese medicine Tripterygium wilfordii Hook. F., exhibits effectiveness in protection against multiple central nervous system (CNS) diseases such as cerebral ischemia, but its influence on lipidomics still remains unclear. Therefore,...

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Bibliographic Details
Main Authors: Maozhu Liu, Mengyuan Chen, Ying Luo, Hong Wang, Haifeng Huang, Zhe Peng, Miaomiao Li, Huizhi Fei, Wen Luo, Junqing Yang
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Molecules
Subjects:
cerebral ischemia/reperfusion injury
celastrol
lipidomics
neuroprotection
UPLC/MS
Online Access:https://www.mdpi.com/1420-3049/26/14/4124

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