Stochastic amplitude-modulated stretching of rabbit <it>flexor digitorum profundus</it> tendons reduces stiffness compared to cyclic loading but does not affect tenocyte metabolism

Stochastic amplitude-modulated stretching of rabbit <it>flexor digitorum profundus</it> tendons reduces stiffness compared to cyclic loading but does not affect tenocyte metabolism

<p>Abstract</p> <p>Background</p> <p>It has been demonstrated that frequency modulation of loading influences cellular response and metabolism in 3D tissues such as cartilage, bone and intervertebral disc. However, the mechano-sensitivity of cells in linear tissues such...

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Bibliographic Details
Main Authors: Steiner Thomas H, Bürki Alexander, Ferguson Stephen J, Gantenbein-Ritter Benjamin
Format: Article
Language:English
Published: BMC 2012-11-01
Series:BMC Musculoskeletal Disorders
Subjects:
Tendon
Tensile stiffness
Stochastic amplitude-modulation
Strain control
Proteoglycan production
Gene expression
Cell activity
Online Access:http://www.biomedcentral.com/1471-2474/13/222

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