HLA-B allele and haplotype diversity among Thai patients identified by PCR-SSOP: evidence for high risk of drug-induced hypersensitivity

HLA-B allele and haplotype diversity among Thai patients identified by PCR-SSOP: evidence for high risk of drug-induced hypersensitivity

BACKGROUND: There are 3 classes of HLA molecules; HLA class I, II and III, of which different classes have different functions. HLA-B gene which belongs to HLA class I play an important role predicting drug hypersensitivity. MATERIALS AND METHODS: Nine hundred and eighty-six Thai subjects who regist...

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Bibliographic Details
Main Author: CHONLAPHAT eSUKASEM
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-01-01
Series:Frontiers in Genetics
Subjects:
Drug Hypersensitivity
HLA-B
Thai
SCARs
PCR-SSOP
Pharmacogenomics markers
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00478/full

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