Crystal Structure of a Variant PAM2 Motif of LARP4B Bound to the MLLE Domain of PABPC1

Eukaryotic cells determine the protein output of their genetic program by regulating mRNA transcription, localization, translation and turnover rates. This regulation is accomplished by an ensemble of RNA-binding proteins (RBPs) that bind to any given mRNA, thus forming mRNPs. Poly(A) binding protei...

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Bibliographic Details
Main Authors: Clemens Grimm, Jann-Patrick Pelz, Cornelius Schneider, Katrin Schäffler, Utz Fischer
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/10/6/872