Early prevention of diabetes microvascular complications in people with hyperglycaemia in Europe. ePREDICE randomized trial. Study protocol, recruitment and selected baseline data.

Early prevention of diabetes microvascular complications in people with hyperglycaemia in Europe. ePREDICE randomized trial. Study protocol, recruitment and selected baseline data.

OBJECTIVES:To assess the effects of early management of hyperglycaemia with antidiabetic drugs plus lifestyle intervention compared with lifestyle alone, on microvascular function in adults with pre-diabetes. METHODS:Trial design: International, multicenter, randomised, partially double-blind, place...

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Main Authors: Rafael Gabriel, Nisa Boukichou Abdelkader, Tania Acosta, Aleksandra Gilis-Januszewska, Ricardo Gómez-Huelgas, Konstantinos Makrilakis, Zdravko Kamenov, Bernhard Paulweber, Ilhan Satman, Predrag Djordjevic, Abdullah Alkandari, Asimina Mitrakou, Nebojsa Lalic, Stephen Colagiuri, Jaana Lindström, Jesús Egido, Andrea Natali, J Carlos Pastor, Yvonne Teuschl, Marcus Lind, Luis Silva, Ruy López-Ridaura, Jaakko Tuomilehto, e-PREDICE Consortium
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0231196

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