Identification of methylation changes associated with positive and negative growth deviance in Gambian infants using a targeted methyl sequencing approach of genomic DNA

Identification of methylation changes associated with positive and negative growth deviance in Gambian infants using a targeted methyl sequencing approach of genomic DNA

Abstract Low birthweight and reduced height gain during infancy (stunting) may arise at least in part from adverse early life environments that trigger epigenetic reprogramming that may favor survival. We examined differential DNA methylation patterns using targeted methyl sequencing of regions regu...

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Bibliographic Details
Main Authors: Claire R. Quilter, Kerry M. Harvey, Julien Bauer, Benjamin M. Skinner, Maria Gomez, Manu Shrivastava, Andrew M. Doel, Saikou Drammeh, David B. Dunger, Sophie E. Moore, Ken K. Ong, Andrew M. Prentice, Robin M. Bernstein, Carole A. Sargent, Nabeel A. Affara
Format: Article
Language:English
Published: Wiley 2021-04-01
Series:FASEB BioAdvances
Subjects:
birthweight
DNA methylation
environmental exposures
stunting
Online Access:https://doi.org/10.1096/fba.2020-00101

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