Potential Roles of microRNAs in the Regulation of Monoamine Oxidase A in the Brain

Potential Roles of microRNAs in the Regulation of Monoamine Oxidase A in the Brain

Monoamine oxidase A (MAO-A) is an enzyme that regulates the levels of monoamine neurotransmitters, such as serotonin, noradrenaline and dopamine and it has been used as a therapeutic target for depression. However, MAO-A inhibitors, which directly acts on MAO-A protein, have limited use due to their...

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Bibliographic Details
Main Authors: Yuki Higuchi, Tomoko Soga, Ishwar S. Parhar
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Molecular Neuroscience
Subjects:
depression
MAO
5-HT
serotonin
non-coding RNA
miRNA
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2018.00339/full

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