The Role of Oxidative Stress in the Development of Systemic Sclerosis Related Vasculopathy

The Role of Oxidative Stress in the Development of Systemic Sclerosis Related Vasculopathy

Systemic sclerosis (SSc) is a rare connective tissue disease characterized by autoimmunity, vasculopathy, and progressive fibrosis typically affecting multiple organs including the skin. SSc often is a lethal disorder, because effective disease-modifying treatment still remains unavailable. Vasculop...

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Bibliographic Details
Main Authors: Amaal E. Abdulle, Gilles F. H. Diercks, Martin Feelisch, Douwe J. Mulder, Harry van Goor
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Physiology
Subjects:
systemic sclerosis
vasculopathy
reactive oxygen species
development
biomarker
intervention
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2018.01177/full

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