Detection of bladder cancer using urinary cell-free DNA and cellular DNA

Detection of bladder cancer using urinary cell-free DNA and cellular DNA

Abstract Background The present study sought to identify a panel of DNA markers for noninvasive diagnosis using cell-free DNA (cfDNA) from urine supernatant or cellular DNA from urine sediments of hematuria patients. A panel of 48 bladder cancer-specific genes was selected. A next-generation sequenc...

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Bibliographic Details
Main Authors: Zhenyu Ou, Kai Li, Ting Yang, Ying Dai, Mohan Chandra, Jun Ning, Yongli Wang, Ran Xu, Tangjie Gao, Yu Xie, Qing He, Yuanwei Li, Qin Lu, Long Wang, Zhuo Song
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Clinical and Translational Medicine
Subjects:
Cell-free DNA
Next-generation sequencing
Bladder cancer
Mutation
Hematuria
Online Access:http://link.springer.com/article/10.1186/s40169-020-0257-2

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