Prenatal Diagnosis of Partial Trisomy 3p (3p21→pter) and Partial Monosomy 11q (11q23→qter) Associated with Abnormal Sonographic Findings of Holoprosencephaly, Orofacial Clefts, Pyelectasis and a Unilateral Duplex Renal System

Prenatal Diagnosis of Partial Trisomy 3p (3p21→pter) and Partial Monosomy 11q (11q23→qter) Associated with Abnormal Sonographic Findings of Holoprosencephaly, Orofacial Clefts, Pyelectasis and a Unilateral Duplex Renal System

Patients with partial trisomy 3p seldom present major dysmorphic features, and holoprosencephaly occurs in only 10% of the cases with partial trisomy 3p. It has been suggested that multiple genetic hits or environmental exposures are required for the clinical expression of holoprosencephaly. At 16 w...

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Bibliographic Details
Main Authors: Chih-Ping Chen, Tzu-Hao Wang, Chyi-Chyang Lin, Fuu-Jen Tsai, Lie-Jiau Hsieh, Wayseen Wang
Format: Article
Language:English
Published: Elsevier 2008-10-01
Series:Journal of the Formosan Medical Association
Subjects:
duplex renal system
holoprosencephaly
orofacial clefts
partial monosomy 11q
partial trisomy 3p
pyelectasis
Online Access:http://www.sciencedirect.com/science/article/pii/S0929664608601977

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http://www.sciencedirect.com/science/article/pii/S0929664608601977

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