Local allergic rhinitis - a big challenge in clinical practice

• Main Authors: Stošović Rajica, Tomić-Spirić Vesna
• Format: Article
• Language: English
• Published: Serbian Medical Society 2021-01-01
• Series: Srpski Arhiv za Celokupno Lekarstvo
• Subjects: local allergic rhinitis; diagnosis; therapy
• Online Access: http://www.doiserbia.nb.rs/img/doi/0370-8179/2021/0370-81792100032S.pdf

Local allergic rhinitis is a new rhinitis phenotype characterized by symptoms similar to allergic rhinitis, in non-atopic patients with a positive nasal allergen provocation test (NAPT). The disease is diagnosed in over 25% of non-atopic patients with rhinitis, marked as non-atopic rhinitis. It most often has perennial and severe symptoms and a progressive course. It is often associated with conjunctivitis and/or asthma. It is necessary to consider local allergic rhinitis in patients with non-atopic rhinitis. The gold standard for diagnosis is a positive NAPT. Pharmacological therapy fails to stop the natural progression and development of comorbidities. Allergen immunotherapy reduces the symptoms, consumption of medicines and increases the tolerance to allergens responsible for local allergic rhinitis. New studies are needed to confirm the curative effects and evaluate the preventive effects of allergen immunotherapy.