Pleiotropic Functions of High Fat Diet in the Etiology of Osteoarthritis.

Obesity is a risk factor for osteoarthritis (OA). To investigate the roles of increased mechanical loading in the onset of obesity-induced OA, knee joints were histologically analyzed after applying a tail suspension (TS) model to a high-fat diet (HFD)-induced OA model. Mice were divided into four g...

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Bibliographic Details
Main Authors: Yoshinori Asou, Munetaka Iwata, Hiroki Ochi, Maierhaba Ailixiding, Zulipiya Aibibula, Jinying Piao, Guangwen Jin, Yasushi Hara, Atsushi Okawa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5017734?pdf=render