Splenic Immune Response Is Down-Regulated in C57BL/6J Mice Fed Eicosapentaenoic Acid and Docosahexaenoic Acid Enriched High Fat Diet

Splenic Immune Response Is Down-Regulated in C57BL/6J Mice Fed Eicosapentaenoic Acid and Docosahexaenoic Acid Enriched High Fat Diet

Dietary n-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are associated with reduction of inflammation, although the mechanisms are poorly understood, especially how the spleen, as a secondary lymphoid organ, is involved. To investigate the effects of EPA and DHA on spleen...

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Bibliographic Details
Main Authors: Nikul K. Soni, Alastair B. Ross, Nathalie Scheers, Otto I. Savolainen, Intawat Nookaew, Britt G. Gabrielsson, Ann-Sofie Sandberg
Format: Article
Language:English
Published: MDPI AG 2017-01-01
Series:Nutrients
Subjects:
eicosapentaenoic acid (EPA)/docosahexaenoic acid (DHA)
spleen transcriptomics
inflammation and immunity
NF-κB
arachidonic acid
Online Access:http://www.mdpi.com/2072-6643/9/1/50

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