Evaluation of the association of C5 with neovascular age-related macular degeneration and polypoidal choroidal vasculopathy

Evaluation of the association of C5 with neovascular age-related macular degeneration and polypoidal choroidal vasculopathy

Abstract Background Neovascular age-related macular degeneration (AMD) and polypoidal choroidal vasculopathy (PCV) are sight-threatening maculopathies with both environmental and genetic risk factors. We have previously shown relative risks posed by genes of the complement pathways to neovascular AM...

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Bibliographic Details
Main Authors: Ke Liu, Li Ma, Timothy Y. Y. Lai, Marten E. Brelen, Pancy O. S. Tam, Clement C. Tham, Chi Pui Pang, Li Jia Chen
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Eye and Vision
Subjects:
Age-related macular degeneration
Polypoidal choroidal vasculopathy
Complete component 5
C5
Genetic association
Single-nucleotide polymorphism
Online Access:http://link.springer.com/article/10.1186/s40662-019-0161-2

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