Expression and functional characterization of chemokine CXCL10 from Nile tilapia (Oreochromis niloticus) in response to bacterial infection and C1q-mediated regulation of monocytes/macrophages activity

Expression and functional characterization of chemokine CXCL10 from Nile tilapia (Oreochromis niloticus) in response to bacterial infection and C1q-mediated regulation of monocytes/macrophages activity

Chemokines are a superfamily of chemotactic cytokines that regulate cell activation, inflammation, and immune defense. In this study, chemokine CXCL10 from Nile tilapia (Oreochromis niloticus) was identified and characterized. The open reading frame of OnCXCL10 is 408 bp encoding polypeptides of 135...

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Bibliographic Details
Main Authors: Meng Chen, Fangfang Yan, Xiayi Wei, Shuo Liu, Biao Han, Li Lin, Jianmin Ye
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:Aquaculture Reports
Subjects:
Oreochromis niloticus
Chemokine CXCL10
Pathogen infection
C1q
Monocytes/macrophages
Online Access:http://www.sciencedirect.com/science/article/pii/S2352513421001940

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