Height Constitutes an Important Predictor of Mortality in End-Stage Renal Disease

Aim. Height is an important determinant of augmentation index (AI) that anticipates cardiovascular prognosis. There is a scanty of the data whether short height predicts survival in patients with end-stage renal diseases, a high risk population. Methods. Fifty two hypertensive patients with type 2 d...

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Main Authors: Tsuneo Takenaka, Takahiko Sato, Hitoshi Hoshi, Nobutaka Kato, Keita Sueyoshi, Masahiro Tsuda, Yusuke Watanabe, Hiroshi Takane, Yoichi Ohno, Hiromichi Suzuki
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Cardiology Research and Practice
Online Access:http://dx.doi.org/10.4061/2011/242353
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spelling doaj-ae3bfa13fcee49829a18655e93ae84d82020-11-24T23:26:23ZengHindawi LimitedCardiology Research and Practice2090-05972011-01-01201110.4061/2011/242353242353Height Constitutes an Important Predictor of Mortality in End-Stage Renal DiseaseTsuneo Takenaka0Takahiko Sato1Hitoshi Hoshi2Nobutaka Kato3Keita Sueyoshi4Masahiro Tsuda5Yusuke Watanabe6Hiroshi Takane7Yoichi Ohno8Hiromichi Suzuki9Department of Medicine, Saitama Medical College, 38 Moro-hongo, Moroyama, Iruma, Saitama 395-0495, JapanDepartment of Medicine, Saitama Medical College, 38 Moro-hongo, Moroyama, Iruma, Saitama 395-0495, JapanDepartment of Medicine, Saitama Medical College, 38 Moro-hongo, Moroyama, Iruma, Saitama 395-0495, JapanDepartment of Medicine, Saitama Medical College, 38 Moro-hongo, Moroyama, Iruma, Saitama 395-0495, JapanDepartment of Medicine, Saitama Medical College, 38 Moro-hongo, Moroyama, Iruma, Saitama 395-0495, JapanDepartment of Medicine, Saitama Medical College, 38 Moro-hongo, Moroyama, Iruma, Saitama 395-0495, JapanDepartment of Medicine, Saitama Medical College, 38 Moro-hongo, Moroyama, Iruma, Saitama 395-0495, JapanDepartment of Medicine, Saitama Medical College, 38 Moro-hongo, Moroyama, Iruma, Saitama 395-0495, JapanDepartment of Medicine, Saitama Medical College, 38 Moro-hongo, Moroyama, Iruma, Saitama 395-0495, JapanDepartment of Medicine, Saitama Medical College, 38 Moro-hongo, Moroyama, Iruma, Saitama 395-0495, JapanAim. Height is an important determinant of augmentation index (AI) that anticipates cardiovascular prognosis. There is a scanty of the data whether short height predicts survival in patients with end-stage renal diseases, a high risk population. Methods. Fifty two hypertensive patients with type 2 diabetic nephropathy receiving hemodialysis and 52 patients with nondiabetic nephropathy were enrolled. In addition to AI estimated with radial artery tonometry, classical cardiovascular risk factors were considered. Patients were followed for 2 years to assess cardiovascular prognosis. Results. Cox hazards regression revealed that both smoking and shortness in height independently contributed to total mortality and indicated that smoking as well as the presence of left ventricular hypertrophy predicted cardiovascular mortality. Our findings implicated that high AI, the presence of diabetes, and low high-density lipoprotein cholesterol were significant contributors to cardiovascular events. Conclusions. Our findings provide new evidence that shortness in height independently contributes to total mortality in hemodialysis patients.http://dx.doi.org/10.4061/2011/242353
collection DOAJ
language English
format Article
sources DOAJ
author Tsuneo Takenaka
Takahiko Sato
Hitoshi Hoshi
Nobutaka Kato
Keita Sueyoshi
Masahiro Tsuda
Yusuke Watanabe
Hiroshi Takane
Yoichi Ohno
Hiromichi Suzuki
spellingShingle Tsuneo Takenaka
Takahiko Sato
Hitoshi Hoshi
Nobutaka Kato
Keita Sueyoshi
Masahiro Tsuda
Yusuke Watanabe
Hiroshi Takane
Yoichi Ohno
Hiromichi Suzuki
Height Constitutes an Important Predictor of Mortality in End-Stage Renal Disease
Cardiology Research and Practice
author_facet Tsuneo Takenaka
Takahiko Sato
Hitoshi Hoshi
Nobutaka Kato
Keita Sueyoshi
Masahiro Tsuda
Yusuke Watanabe
Hiroshi Takane
Yoichi Ohno
Hiromichi Suzuki
author_sort Tsuneo Takenaka
title Height Constitutes an Important Predictor of Mortality in End-Stage Renal Disease
title_short Height Constitutes an Important Predictor of Mortality in End-Stage Renal Disease
title_full Height Constitutes an Important Predictor of Mortality in End-Stage Renal Disease
title_fullStr Height Constitutes an Important Predictor of Mortality in End-Stage Renal Disease
title_full_unstemmed Height Constitutes an Important Predictor of Mortality in End-Stage Renal Disease
title_sort height constitutes an important predictor of mortality in end-stage renal disease
publisher Hindawi Limited
series Cardiology Research and Practice
issn 2090-0597
publishDate 2011-01-01
description Aim. Height is an important determinant of augmentation index (AI) that anticipates cardiovascular prognosis. There is a scanty of the data whether short height predicts survival in patients with end-stage renal diseases, a high risk population. Methods. Fifty two hypertensive patients with type 2 diabetic nephropathy receiving hemodialysis and 52 patients with nondiabetic nephropathy were enrolled. In addition to AI estimated with radial artery tonometry, classical cardiovascular risk factors were considered. Patients were followed for 2 years to assess cardiovascular prognosis. Results. Cox hazards regression revealed that both smoking and shortness in height independently contributed to total mortality and indicated that smoking as well as the presence of left ventricular hypertrophy predicted cardiovascular mortality. Our findings implicated that high AI, the presence of diabetes, and low high-density lipoprotein cholesterol were significant contributors to cardiovascular events. Conclusions. Our findings provide new evidence that shortness in height independently contributes to total mortality in hemodialysis patients.
url http://dx.doi.org/10.4061/2011/242353
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