Height Constitutes an Important Predictor of Mortality in End-Stage Renal Disease
Aim. Height is an important determinant of augmentation index (AI) that anticipates cardiovascular prognosis. There is a scanty of the data whether short height predicts survival in patients with end-stage renal diseases, a high risk population. Methods. Fifty two hypertensive patients with type 2 d...
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doaj-ae3bfa13fcee49829a18655e93ae84d82020-11-24T23:26:23ZengHindawi LimitedCardiology Research and Practice2090-05972011-01-01201110.4061/2011/242353242353Height Constitutes an Important Predictor of Mortality in End-Stage Renal DiseaseTsuneo Takenaka0Takahiko Sato1Hitoshi Hoshi2Nobutaka Kato3Keita Sueyoshi4Masahiro Tsuda5Yusuke Watanabe6Hiroshi Takane7Yoichi Ohno8Hiromichi Suzuki9Department of Medicine, Saitama Medical College, 38 Moro-hongo, Moroyama, Iruma, Saitama 395-0495, JapanDepartment of Medicine, Saitama Medical College, 38 Moro-hongo, Moroyama, Iruma, Saitama 395-0495, JapanDepartment of Medicine, Saitama Medical College, 38 Moro-hongo, Moroyama, Iruma, Saitama 395-0495, JapanDepartment of Medicine, Saitama Medical College, 38 Moro-hongo, Moroyama, Iruma, Saitama 395-0495, JapanDepartment of Medicine, Saitama Medical College, 38 Moro-hongo, Moroyama, Iruma, Saitama 395-0495, JapanDepartment of Medicine, Saitama Medical College, 38 Moro-hongo, Moroyama, Iruma, Saitama 395-0495, JapanDepartment of Medicine, Saitama Medical College, 38 Moro-hongo, Moroyama, Iruma, Saitama 395-0495, JapanDepartment of Medicine, Saitama Medical College, 38 Moro-hongo, Moroyama, Iruma, Saitama 395-0495, JapanDepartment of Medicine, Saitama Medical College, 38 Moro-hongo, Moroyama, Iruma, Saitama 395-0495, JapanDepartment of Medicine, Saitama Medical College, 38 Moro-hongo, Moroyama, Iruma, Saitama 395-0495, JapanAim. Height is an important determinant of augmentation index (AI) that anticipates cardiovascular prognosis. There is a scanty of the data whether short height predicts survival in patients with end-stage renal diseases, a high risk population. Methods. Fifty two hypertensive patients with type 2 diabetic nephropathy receiving hemodialysis and 52 patients with nondiabetic nephropathy were enrolled. In addition to AI estimated with radial artery tonometry, classical cardiovascular risk factors were considered. Patients were followed for 2 years to assess cardiovascular prognosis. Results. Cox hazards regression revealed that both smoking and shortness in height independently contributed to total mortality and indicated that smoking as well as the presence of left ventricular hypertrophy predicted cardiovascular mortality. Our findings implicated that high AI, the presence of diabetes, and low high-density lipoprotein cholesterol were significant contributors to cardiovascular events. Conclusions. Our findings provide new evidence that shortness in height independently contributes to total mortality in hemodialysis patients.http://dx.doi.org/10.4061/2011/242353 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Tsuneo Takenaka Takahiko Sato Hitoshi Hoshi Nobutaka Kato Keita Sueyoshi Masahiro Tsuda Yusuke Watanabe Hiroshi Takane Yoichi Ohno Hiromichi Suzuki |
spellingShingle |
Tsuneo Takenaka Takahiko Sato Hitoshi Hoshi Nobutaka Kato Keita Sueyoshi Masahiro Tsuda Yusuke Watanabe Hiroshi Takane Yoichi Ohno Hiromichi Suzuki Height Constitutes an Important Predictor of Mortality in End-Stage Renal Disease Cardiology Research and Practice |
author_facet |
Tsuneo Takenaka Takahiko Sato Hitoshi Hoshi Nobutaka Kato Keita Sueyoshi Masahiro Tsuda Yusuke Watanabe Hiroshi Takane Yoichi Ohno Hiromichi Suzuki |
author_sort |
Tsuneo Takenaka |
title |
Height Constitutes an Important Predictor of Mortality in End-Stage Renal Disease |
title_short |
Height Constitutes an Important Predictor of Mortality in End-Stage Renal Disease |
title_full |
Height Constitutes an Important Predictor of Mortality in End-Stage Renal Disease |
title_fullStr |
Height Constitutes an Important Predictor of Mortality in End-Stage Renal Disease |
title_full_unstemmed |
Height Constitutes an Important Predictor of Mortality in End-Stage Renal Disease |
title_sort |
height constitutes an important predictor of mortality in end-stage renal disease |
publisher |
Hindawi Limited |
series |
Cardiology Research and Practice |
issn |
2090-0597 |
publishDate |
2011-01-01 |
description |
Aim. Height is an important determinant of augmentation index (AI) that anticipates cardiovascular prognosis. There is a scanty of the data whether short height predicts survival in patients with end-stage renal diseases, a high risk population. Methods. Fifty two hypertensive patients with type 2 diabetic nephropathy receiving hemodialysis and 52 patients with nondiabetic nephropathy were enrolled. In addition to AI estimated with radial artery tonometry, classical cardiovascular risk factors were considered. Patients were followed for 2 years to assess cardiovascular prognosis. Results. Cox hazards regression revealed that both smoking and shortness in height independently contributed to total mortality and indicated that smoking as well as the presence of left ventricular hypertrophy predicted cardiovascular mortality. Our findings implicated that high AI, the presence of diabetes, and low high-density lipoprotein cholesterol were significant contributors to cardiovascular events. Conclusions. Our findings provide new evidence that shortness in height independently contributes to total mortality in hemodialysis patients. |
url |
http://dx.doi.org/10.4061/2011/242353 |
work_keys_str_mv |
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