Reassessing the Role of the Type II MqsRA Toxin-Antitoxin System in Stress Response and Biofilm Formation: mqsA Is Transcriptionally Uncoupled from mqsR

Reassessing the Role of the Type II MqsRA Toxin-Antitoxin System in Stress Response and Biofilm Formation: mqsA Is Transcriptionally Uncoupled from mqsR

There is growing controversy regarding the role of chromosomal toxin-antitoxin systems in bacterial physiology. mqsRA is a peculiar toxin-antitoxin system, as the gene encoding the toxin precedes that of the antitoxin. This system was previously shown to play a role in stress response and biofilm fo...

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Bibliographic Details
Main Authors: Nathan Fraikin, Clothilde J. Rousseau, Nathalie Goeders, Laurence Van Melderen
Format: Article
Language:English
Published: American Society for Microbiology 2019-12-01
Series:mBio
Subjects:
mqsr
mqsa
ta system
stress adaptation
biofilm
global regulation
persistence
rpos
stress response
toxin-antitoxin
Online Access:https://doi.org/10.1128/mBio.02678-19

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