Clock genes and behavioral responses to light are altered in a mouse model of diabetic retinopathy.

There is increasing evidence that melanopsin-expressing ganglion cells (ipRGCs) are altered in retinal pathologies. Using a streptozotocin-induced (STZ) model of diabetes, we investigated the impact of diabetic retinopathy on non-visual functions by analyzing ipRGCs morphology and light-induced c-Fo...

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Bibliographic Details
Main Authors: Hasna Lahouaoui, Christine Coutanson, Howard M Cooper, Mohamed Bennis, Ouria Dkhissi-Benyahya
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4089924?pdf=render