Enhancing both oral bioavailability and brain penetration of puerarin using borneol in combination with preparation technologies

Enhancing both oral bioavailability and brain penetration of puerarin using borneol in combination with preparation technologies

Now there are few good oral preparations of puerarin used in cerebrovascular diseases because of its poor oral absorption caused by the low water solubility and the poor penetration into brain. In this study, three oral formulations of puerarin, nanocrystals suspension (NCS), inclusion compounds sol...

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Bibliographic Details
Main Authors: Tao Yi, Dandan Tang, Fan Wang, Jiqiong Zhang, Jiao Zhang, Jirui Wang, Xiaoyu Xu, Jifen Zhang
Format: Article
Language:English
Published: Taylor & Francis Group 2017-01-01
Series:Drug Delivery
Subjects:
puerarin
borneol
nanocrystals
inclusion compounds
self-microemulsifying drug delivery system
Online Access:http://dx.doi.org/10.1080/10717544.2016.1259372

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