P50, the small subunit of DNA polymerase delta, is required for mediation of the interaction of polymerase delta subassemblies with PCNA.

Mammalian DNA polymerase δ (pol δ), a four-subunit enzyme, plays a crucial and versatile role in DNA replication and various DNA repair processes. Its function as a chromosomal DNA polymerase is dependent on the association with proliferating cell nuclear antigen (PCNA) which functions as a molecula...

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Bibliographic Details
Main Authors: Yujue Wang, Qian Zhang, Huiqing Chen, Xiao Li, Weijun Mai, Keping Chen, Sufang Zhang, Ernest Y C Lee, Marietta Y W T Lee, Yajing Zhou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22073260/?tool=EBI