E3 ligase activity of Carboxyl terminus of Hsc70 interacting protein (CHIP) in Wharton's jelly derived mesenchymal stem cells improves their persistence under hyperglycemic stress and promotes the prophylactic effects against diabetic cardiac damages

E3 ligase activity of Carboxyl terminus of Hsc70 interacting protein (CHIP) in Wharton's jelly derived mesenchymal stem cells improves their persistence under hyperglycemic stress and promotes the prophylactic effects against diabetic cardiac damages

Abstract Recent studies indicate that umbilical cord stem cells are cytoprotective against several disorders. One critical limitation in using stem cells is reduction in their viability under stressful conditions, such as diabetes. However, the molecular intricacies responsible for diabetic conditio...

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Bibliographic Details
Main Authors: Ayaz Ali, Wei‐Wen Kuo, Chia‐Hua Kuo, Jeng‐Fan Lo, Michael Y. C. Chen, Jayasimha R. Daddam, Tsung‐Jung Ho, Vijaya Padma Viswanadha, Marthandam Asokan Shibu, Chih‐Yang Huang
Format: Article
Language:English
Published: Wiley 2021-09-01
Series:Bioengineering & Translational Medicine
Subjects:
apoptosis
carboxyl terminus of Hsc70 interacting protein
diabetes
phosphatase and tensin homolog
Wharton's jelly derived mesenchymal stem cells
Online Access:https://doi.org/10.1002/btm2.10234

Internet

https://doi.org/10.1002/btm2.10234

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