Bisdemethoxycurcumin Increases Sirt1 to Antagonize t-BHP-Induced Premature Senescence in WI38 Fibroblast Cells

Curcuminoids are well known for their capabilities to combat risk factors that are associated with ageing and cellular senescence. Recent reports have demonstrated that curcuminoids can extend the lifespan of model organisms. However, the underlying mechanisms by which these polyphenic compounds exe...

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Bibliographic Details
Main Authors: Ying-Bo Li, Zhang-Feng Zhong, Mei-Wan Chen, Jiao-Lin Bao, Guo-Sheng Wu, Qing-Wen Zhang, Simon Ming-Yuen Lee, Pui-Man Hoi, Yi-Tao Wang
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Evidence-Based Complementary and Alternative Medicine
Online Access:http://dx.doi.org/10.1155/2013/851714