Calcium imaging reveals glial involvement in transcranial direct current stimulation-induced plasticity in mouse brain

Calcium imaging reveals glial involvement in transcranial direct current stimulation-induced plasticity in mouse brain

While transcranical direct current stimulation (tDCS) is used in clinical setting, its cellular mechanism of action is unclear. Here, Hajime Hirase and colleagues visualize cellular response in mouse brain to tDCS and show robust astrocyte activation that coincide with plasticity changes.

Bibliographic Details
Main Authors: Hiromu Monai, Masamichi Ohkura, Mika Tanaka, Yuki Oe, Ayumu Konno, Hirokazu Hirai, Katsuhiko Mikoshiba, Shigeyoshi Itohara, Junichi Nakai, Youichi Iwai, Hajime Hirase
Format: Article
Language:English
Published: Nature Publishing Group 2016-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms11100
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spelling doaj-ae0783c67e994315983234e3e289a89c2021-05-11T11:02:45ZengNature Publishing GroupNature Communications2041-17232016-03-017111010.1038/ncomms11100Calcium imaging reveals glial involvement in transcranial direct current stimulation-induced plasticity in mouse brainHiromu Monai0Masamichi Ohkura1Mika Tanaka2Yuki Oe3Ayumu Konno4Hirokazu Hirai5Katsuhiko Mikoshiba6Shigeyoshi Itohara7Junichi Nakai8Youichi Iwai9Hajime Hirase10RIKEN Brain Science InstituteBrain Science Institute, Saitama UniversityRIKEN Brain Science InstituteRIKEN Brain Science InstituteDepartment of Neurophysiology and Neural Repair, Gunma University Graduate School of MedicineDepartment of Neurophysiology and Neural Repair, Gunma University Graduate School of MedicineRIKEN Brain Science InstituteRIKEN Brain Science InstituteBrain Science Institute, Saitama UniversityRIKEN Brain Science InstituteRIKEN Brain Science InstituteWhile transcranical direct current stimulation (tDCS) is used in clinical setting, its cellular mechanism of action is unclear. Here, Hajime Hirase and colleagues visualize cellular response in mouse brain to tDCS and show robust astrocyte activation that coincide with plasticity changes.https://doi.org/10.1038/ncomms11100
collection DOAJ
language English
format Article
sources DOAJ
author Hiromu Monai
Masamichi Ohkura
Mika Tanaka
Yuki Oe
Ayumu Konno
Hirokazu Hirai
Katsuhiko Mikoshiba
Shigeyoshi Itohara
Junichi Nakai
Youichi Iwai
Hajime Hirase
spellingShingle Hiromu Monai
Masamichi Ohkura
Mika Tanaka
Yuki Oe
Ayumu Konno
Hirokazu Hirai
Katsuhiko Mikoshiba
Shigeyoshi Itohara
Junichi Nakai
Youichi Iwai
Hajime Hirase
Calcium imaging reveals glial involvement in transcranial direct current stimulation-induced plasticity in mouse brain
Nature Communications
author_facet Hiromu Monai
Masamichi Ohkura
Mika Tanaka
Yuki Oe
Ayumu Konno
Hirokazu Hirai
Katsuhiko Mikoshiba
Shigeyoshi Itohara
Junichi Nakai
Youichi Iwai
Hajime Hirase
author_sort Hiromu Monai
title Calcium imaging reveals glial involvement in transcranial direct current stimulation-induced plasticity in mouse brain
title_short Calcium imaging reveals glial involvement in transcranial direct current stimulation-induced plasticity in mouse brain
title_full Calcium imaging reveals glial involvement in transcranial direct current stimulation-induced plasticity in mouse brain
title_fullStr Calcium imaging reveals glial involvement in transcranial direct current stimulation-induced plasticity in mouse brain
title_full_unstemmed Calcium imaging reveals glial involvement in transcranial direct current stimulation-induced plasticity in mouse brain
title_sort calcium imaging reveals glial involvement in transcranial direct current stimulation-induced plasticity in mouse brain
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2016-03-01
description While transcranical direct current stimulation (tDCS) is used in clinical setting, its cellular mechanism of action is unclear. Here, Hajime Hirase and colleagues visualize cellular response in mouse brain to tDCS and show robust astrocyte activation that coincide with plasticity changes.
url https://doi.org/10.1038/ncomms11100
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