Innate immune responses to AAV vectors

Innate immune responses to AAV vectors

Gene replacement therapy by in vivo delivery of adeno-associated virus (AAV) is attractive as a potential treatment for a variety of genetic disorders. However, while AAV has been used successfully in many models, other experiments in clinical trials and in animal models have been hampered by undesi...

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Bibliographic Details
Main Authors: Geoffrey L Rogers, Ashley T Martino, George V Aslanidi, Giridhara R Jayandharan, Arun eSrivastava, Roland W. Herzog
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-09-01
Series:Frontiers in Microbiology
Subjects:
Gene Therapy
innate immunity
AAV vectors
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2011.00194/full

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