Instructing cells with programmable peptide DNA hybrids

The extracellular matrix can affect cell behaviour both physically and biochemically. Here, the authors developed a substrate that is based on peptides and nucleic acids hybrids that can dynamically present signals upon demand which regulate cell adhesion and migration, thereby controlling cell orga...

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Main Authors:	Ronit Freeman, Nicholas Stephanopoulos, Zaida Álvarez, Jacob A Lewis, Shantanu Sur, Chris M Serrano, Job Boekhoven, Sungsoo S. Lee, Samuel I. Stupp
Format:	Article
Language:	English
Published:	Nature Publishing Group 2017-07-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/ncomms15982

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spelling	doaj-adec0b74d8f044eba6a16b4902f1965a2021-05-11T07:51:14ZengNature Publishing GroupNature Communications2041-17232017-07-018111110.1038/ncomms15982Instructing cells with programmable peptide DNA hybridsRonit Freeman0Nicholas Stephanopoulos1Zaida Álvarez2Jacob A Lewis3Shantanu Sur4Chris M Serrano5Job Boekhoven6Sungsoo S. Lee7Samuel I. Stupp8Simpson Querrey Institute for BioNanotechnology, Northwestern UniversitySimpson Querrey Institute for BioNanotechnology, Northwestern UniversitySimpson Querrey Institute for BioNanotechnology, Northwestern UniversityDepartment of Biomedical Engineering, Northwestern UniversitySimpson Querrey Institute for BioNanotechnology, Northwestern UniversityDepartment of Materials Science and Engineering, Northwestern UniversitySimpson Querrey Institute for BioNanotechnology, Northwestern UniversitySimpson Querrey Institute for BioNanotechnology, Northwestern UniversitySimpson Querrey Institute for BioNanotechnology, Northwestern UniversityThe extracellular matrix can affect cell behaviour both physically and biochemically. Here, the authors developed a substrate that is based on peptides and nucleic acids hybrids that can dynamically present signals upon demand which regulate cell adhesion and migration, thereby controlling cell organisation.https://doi.org/10.1038/ncomms15982
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Ronit Freeman Nicholas Stephanopoulos Zaida Álvarez Jacob A Lewis Shantanu Sur Chris M Serrano Job Boekhoven Sungsoo S. Lee Samuel I. Stupp
spellingShingle	Ronit Freeman Nicholas Stephanopoulos Zaida Álvarez Jacob A Lewis Shantanu Sur Chris M Serrano Job Boekhoven Sungsoo S. Lee Samuel I. Stupp Instructing cells with programmable peptide DNA hybrids Nature Communications
author_facet	Ronit Freeman Nicholas Stephanopoulos Zaida Álvarez Jacob A Lewis Shantanu Sur Chris M Serrano Job Boekhoven Sungsoo S. Lee Samuel I. Stupp
author_sort	Ronit Freeman
title	Instructing cells with programmable peptide DNA hybrids
title_short	Instructing cells with programmable peptide DNA hybrids
title_full	Instructing cells with programmable peptide DNA hybrids
title_fullStr	Instructing cells with programmable peptide DNA hybrids
title_full_unstemmed	Instructing cells with programmable peptide DNA hybrids
title_sort	instructing cells with programmable peptide dna hybrids
publisher	Nature Publishing Group
series	Nature Communications
issn	2041-1723
publishDate	2017-07-01
description	The extracellular matrix can affect cell behaviour both physically and biochemically. Here, the authors developed a substrate that is based on peptides and nucleic acids hybrids that can dynamically present signals upon demand which regulate cell adhesion and migration, thereby controlling cell organisation.
url	https://doi.org/10.1038/ncomms15982
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Instructing cells with programmable peptide DNA hybrids

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