COMBO-FISH Enables High Precision Localization Microscopy as a Prerequisite for Nanostructure Analysis of Genome Loci

COMBO-FISH Enables High Precision Localization Microscopy as a Prerequisite for Nanostructure Analysis of Genome Loci

With the completeness of genome databases, it has become possible to develop a novel FISH (Fluorescence in Situ Hybridization) technique called COMBO-FISH (COMBinatorial Oligo FISH). In contrast to other FISH techniques, COMBO-FISH makes use of a bioinformatics approach for probe set design. By mean...

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Bibliographic Details
Main Authors: Rainer Kaufmann, Christoph Cremer, Jörg Hoheisel, Anette Jacob, Eberhard Schmitt, Patrick Müller, Michael Hausmann
Format: Article
Language:English
Published: MDPI AG 2010-10-01
Series:International Journal of Molecular Sciences
Subjects:
COMBO-FISH
combinatorial oligo fluorescence in situ hybridization, computer based probe selection
PNA
SPDM
spectral precision distance/position determination microscopy
localization microscopy
nanostructure analysis of the genome
Online Access:http://www.mdpi.com/1422-0067/11/10/4094/

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