Lumbar and ventricular CSF concentrations of extracellular matrix proteins before and after shunt surgery in idiopathic normal pressure hydrocephalus

Lumbar and ventricular CSF concentrations of extracellular matrix proteins before and after shunt surgery in idiopathic normal pressure hydrocephalus

Abstract Background Idiopathic normal pressure hydrocephalus (iNPH) is a reversible CNS disease characterized by disturbed cerebrospinal fluid (CSF) dynamics. Changes in the extracellular matrix (ECM) composition might be involved in the pathophysiology of iNPH. The aim of this study was to explore...

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Bibliographic Details
Main Authors: Karolina Minta, Anna Jeppsson, Gunnar Brinkmalm, Erik Portelius, Henrik Zetterberg, Kaj Blennow, Mats Tullberg, Ulf Andreasson
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Fluids and Barriers of the CNS
Subjects:
Brevican
Idiopathic normal pressure hydrocephalus
Immunoassay
Mass spectrometry
Matrix metalloproteinase
Neurocan
Online Access:https://doi.org/10.1186/s12987-021-00256-1

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