Preferential release of newly synthesized insulin assessed by a multi-label reporter system using pancreatic β-cell line MIN6.

Preferential release of newly synthesized insulin assessed by a multi-label reporter system using pancreatic β-cell line MIN6.

Newly synthesized hormones have been suggested to be preferentially secreted by various neuroendocrine cells. This observation indicates that there is a distinct population of secretory granules containing new and old hormones. Recent development of fluorescent timer proteins used in bovine adrenal...

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Bibliographic Details
Main Authors: Ni Hou, Hideo Mogami, Chisato Kubota-Murata, Meng Sun, Toshiyuki Takeuchi, Seiji Torii
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3485036?pdf=render

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