Recent progress in TGF-β inhibitors for cancer therapy

Recent progress in TGF-β inhibitors for cancer therapy

Transforming growth factor-β (TGF-β) is a multifunctional cytokine that is involved in proliferation, metastasis, and many other important processes in malignancy. Inhibitors targeting TGF-β have been considered by pharmaceutical companies for cancer therapy, and some of them are in clinical trial n...

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Bibliographic Details
Main Authors: Cheng-Yi Huang, Chih-Ling Chung, Tsung-Hui Hu, Jih-Jung Chen, Pei-Feng Liu, Chun-Lin Chen
Format: Article
Language:English
Published: Elsevier 2021-02-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Small-molecule inhibitor
Cancer therapy
TGF-β inhibitor
Endocytosis
Lipid raft
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332220312385

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