T cell epitope immunotherapy induces a CD4+ T cell population with regulatory activity.

BACKGROUND: Synthetic peptides, representing CD4(+) T cell epitopes, derived from the primary sequence of allergen molecules have been used to down-regulate allergic inflammation in sensitised individuals. Treatment of allergic diseases with peptides may offer substantial advantages over treatment w...

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Bibliographic Details
Main Authors: Adrienne Verhoef, Clare Alexander, A Barry Kay, Mark Larché
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2005-03-01
Series:PLoS Medicine
Online Access:http://europepmc.org/articles/PMC1069669?pdf=render