Long-term Treatment with Low-Dose Caffeine Worsens BPSD-Like Profile in 3xTg-AD Mice Model of Alzheimer’s Disease and Affects Mice with Normal Aging

Coffee or caffeine has recently been suggested as prophylaxis for dementia. Although memory problems are hallmarks of Alzheimer’s disease, this dementia is also characterized by neuropsychiatric symptoms called Behavioral and Psychological Symptoms of Dementia (BPSD). The impact of preventive/therap...

Full description

Bibliographic Details
Main Authors:	Raquel Baeta-Corral, Björn Johansson, Lydia Giménez-Llort
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2018-02-01
Series:	Frontiers in Pharmacology
Subjects:	aging anxiety memory NPS BPSD circadian activity
Online Access:	http://journal.frontiersin.org/article/10.3389/fphar.2018.00079/full

Similar Items

Digging Signatures in 13-Month-Old 3xTg-AD Mice for Alzheimer's Disease and Its Disruption by Isolation Despite Social Life Since They Were Born
by: Lydia Gimenez-Llort, et al.
Published: (2021-01-01)

Editorial: Pharmacology of BPSD (Behavioral and Psychological Symptoms of Dementia)
by: Lydia Giménez-Llort, et al.
Published: (2021-06-01)

Impact of Chronic Risperidone Use on Behavior and Survival of 3xTg-AD Mice Model of Alzheimer’s Disease and Mice With Normal Aging
by: Virginia Torres-Lista, et al.
Published: (2019-09-01)

Preserved Thermal Pain in 3xTg-AD Mice With Increased Sensory-Discriminative Pain Sensitivity in Females but Affective-Emotional Dimension in Males as Early Sex-Specific AD-Phenotype Biomarkers
by: Toni Cañete, et al.
Published: (2021-07-01)

Gender-Specific Neuroimmunoendocrine Response to Treadmill Exercise in 3xTg-AD Mice
by: Lydia Giménez-Llort, et al.
Published: (2010-01-01)

Clock/Sleep-Dependent Learning and Memory in Male 3xTg-AD Mice at Advanced Disease Stages and Extrinsic Effects of Huprine X and the Novel Multitarget Agent AVCRI104P3
by: Lydia Giménez-Llort, et al.
Published: (2021-03-01)

BPSD following traumatic brain injury
by: Renato Anghinah, et al.

Vårdpersonalens upplevelser av att vårda personer med Beteendemässiga och Psykiska Symtom vid Demens (BPSD)
by: Östgård, Kristina
Published: (2014)

Genotype Load Modulates Amyloid Burden and Anxiety-Like Patterns in Male 3xTg-AD Survivors despite Similar Neuro-Immunoendocrine, Synaptic and Cognitive Impairments
by: Aida Muntsant, et al.
Published: (2021-06-01)

Att arbeta med BPSD-registret : vårdpersonalens upplevelse
by: Bodén, Anna
Published: (2016)

Personalutbildning – effektiv strategi vid oro/agitation kopplad till BPSD hos brukare som bor i särskilda boenden?
by: Sjöberg, Andreas, et al.
Published: (2014)

T-type Ca2+ channel enhancer SAK3 administration improves the BPSD-like behaviors in AppNL−G-F/NL−G-F knock-in mice
by: Tomohide Degawa, et al.
Published: (2021-05-01)

Behavioral and Psychological Symptoms in Dementia (BPSD) and the Use of Antipsychotics
by: Valeria Calsolaro, et al.
Published: (2021-03-01)

Betydelsen av identifiering och behandling av smärta hos personer med demens och personer med BPSD : en litteraturöversikt
by: Franzén, Sanna, et al.
Published: (2016)

Olfactory Signatures in the Food Finding Test in Mice With Normal and Alzheimer’s Disease-Pathological Aging With Special Concerns on the Effects of Social Isolation
by: Daniela Marín-Pardo, et al.
Published: (2021-10-01)

IL-6 Trans-Signaling in the Brain Influences the Metabolic Phenotype of the 3xTg-AD Mouse Model of Alzheimer’s Disease
by: Anna Escrig, et al.
Published: (2020-07-01)

Dopaminergic dysfunction in the 3xTg-AD mice model of Alzheimer’s disease
by: Yesica Gloria, et al.
Published: (2021-09-01)

Behavioral and Psychological Symptoms of Dementia (BPSD): Clinical Characterization and Genetic Correlates in an Italian Alzheimer’s Disease Cohort
by: Catia Scassellati, et al.
Published: (2020-08-01)

An Ethnography Study of a Viral YouTube Educational Video in Ecuador: Dealing With Death and Grief in Times of COVID-19
by: Lydia Giménez-Llort, et al.
Published: (2021-07-01)

SJUKSKÖTERSKANS BEMÖTANDE TILL PATIENTER MED DEMENS SOM UPPVISAR SYMTOM PÅ BPSD
by: Svensson, Linda, et al.
Published: (2018)

Hypertension Accelerates Alzheimer’s Disease-Related Pathologies in Pigs and 3xTg Mice
by: Yao-Hsiang Shih, et al.
Published: (2018-03-01)

Effekten av interventioner för den äldre personen med beteendemässiga och psykiska symtom vid demens (BPSD) inom äldreomsorgen : En litteraturstudie
by: Norman, Cajsa, et al.
Published: (2020)

Early Onset of Sex-Dependent Mitochondrial Deficits in the Cortex of 3xTg Alzheimer’s Mice
by: Jelena Djordjevic, et al.
Published: (2020-06-01)

Foundations and Applications of Logotherapy to Improve Mental Health of Immigrant Populations in the Third Millennium
by: Shirin Rahgozar, et al.
Published: (2020-06-01)

Precision Medicine of Sodium Benzoate for the Treatment of Behavioral and Psychological Symptoms of Dementia (BPSD)
by: Lin CH, et al.
Published: (2020-02-01)

UPON TYPE, FREQUENCY AND SOME CLINICAL ASPECTS OF PSYCHOTIC SYMPTOMS IN ALZHEIMER’S DISEASE
by: Mariana Arnaudova
Published: (2011-12-01)

Antipsychotic Treatment of Behavioral and Psychological Symptoms of Dementia (BPSD): Management of Extrapyramidal Side Effects
by: Yukihiro Ohno, et al.
Published: (2019-09-01)

Treatment of Alzheimer's disease with anti-homocysteic acid antibody in 3xTg-AD male mice.
by: Tohru Hasegawa, et al.
Published: (2010-01-01)

Treatment of late-stage Alzheimer's disease with folate derivatives in the 3xTg-AD mice model
by: Hung-Cheng Hsu, et al.
Published: (2013)

Amelioration of BPSD-Like Phenotype and Cognitive Decline in SAMP8 Mice Model Accompanied by Molecular Changes after Treatment with I<sub>2</sub>-Imidazoline Receptor Ligand MCR5
by: Foteini Vasilopoulou, et al.
Published: (2020-05-01)

Att se människan bakom sjukdomen är som att lösa en gåta : En litteraturbaserad studie om vårdpersonalens erfarenheter av personcentrerad vård vid beteendemässiga och psykiska symtom vid demens (BPSD)
by: Lind, Maria, et al.
Published: (2018)

PasoDoble, a Proposed Dance/Music for People With Parkinson's Disease and Their Caregivers
by: Lydia Giménez-Llort, et al.
Published: (2020-11-01)

Sounds of Silence in Times of COVID-19: Distress and Loss of Cardiac Coherence in People With Misophonia Caused by Real, Imagined or Evoked Triggering Sounds
by: Antonia Ferrer-Torres, et al.
Published: (2021-06-01)

Effekter av icke-farmakologiska metoder vid beteendemässiga och psykiska symtom hos personer som lever med Alzheimers sjukdom : En litteraturöversikt
by: Tasci,, Gulseren, et al.
Published: (2016)

Behavioral and psychological symptoms in dementia is not a unitary concept: A critical review with emphasis on Alzheimer's disease
by: Jerson Laks, et al.

Impact of Social Isolation on the Behavioral, Functional Profiles, and Hippocampal Atrophy Asymmetry in Dementia in Times of Coronavirus Pandemic (COVID-19): A Translational Neuroscience Approach
by: Aida Muntsant, et al.
Published: (2020-11-01)

Decreased Behavioral Abnormalities After Treatment with Combined Donepezil and Yokukansankachimpihange in Alzheimer Disease: An Observational Study. The Osaki-Tajiri Project
by: Kenichi Meguro, et al.
Published: (2018-09-01)

General practitioners’ knowledge, attitudes and experiences of managing behavioural and psychological symptoms of dementia: protocol of a mixed methods systematic review and meta-ethnography
by: Aisling A. Jennings, et al.
Published: (2018-04-01)

Omvårdnadsåtgärder vid beteendemässiga och psykiska symptomvid demenssjukdom : En litteratur studie
by: Kianpoor, Fariba, et al.
Published: (2012)

Interaction between anti-Alzheimer and antipsychotic drugs in modulating extrapyramidal motor disorders in mice
by: Saki Shimizu, et al.
Published: (2015-04-01)

Cannot write session to /tmp/vufind_sessions/sess_c2kc6m00k7r60dtjd2la8na3sd