Limitations of Animal Studies for Predicting Toxicity in Clinical Trials
Summary: Animal testing is used in pharmaceutical and industrial research to predict human toxicity, and yet analysis suggests that animal models are poor predictors of drug safety in humans. The cost of animal research is high—in dollars, delays in drug approval, and in the loss of potentially bene...
Main Author: | Gail A. Van Norman, MD |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2019-11-01
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Series: | JACC: Basic to Translational Science |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2452302X1930316X |
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