Peripherally misfolded proteins exacerbate ischemic stroke-induced neuroinflammation and brain injury

Peripherally misfolded proteins exacerbate ischemic stroke-induced neuroinflammation and brain injury

Abstract Background Protein aggregates can be found in peripheral organs, such as the heart, kidney, and pancreas, but little is known about the impact of peripherally misfolded proteins on neuroinflammation and brain functional recovery following ischemic stroke. Methods Here, we studied the ischem...

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Bibliographic Details
Main Authors: Yanying Liu, Kalpana Subedi, Aravind Baride, Svetlana Romanova, Eduardo Callegari, Christa C. Huber, Xuejun Wang, Hongmin Wang
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Journal of Neuroinflammation
Subjects:
Heart
Peripheral
Brain
Crosstalk
Ischemia
Stroke
Online Access:https://doi.org/10.1186/s12974-021-02081-7

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