Long-Term Azithromycin Maintenance Treatment in Patients with Frequent Exacerbations of Chronic Obstructive Pulmonary Disease

• Main Authors: Talman S, Uzun S, Djamin RS, Baart SJ, Grootenboers MJJH, Aerts J, van der Eerden M
• Format: Article
• Language: English
• Published: Dove Medical Press 2021-03-01
• Series: International Journal of COPD
• Subjects: copd; exacerbations; macrolide; maintenance-therapy
• Online Access: https://www.dovepress.com/long-term-azithromycin-maintenance-treatment-in-patients-with-frequent-peer-reviewed-article-COPD
• ISSN: 1178-2005

Sander Talman,1 Sevim Uzun,2 Remco S Djamin,1 Sara J Baart,3 Marco JJH Grootenboers,1 Joachim Aerts,2 Menno van der Eerden2 1Amphia Hospital Breda, Department of Pulmonary Medicine, Breda, 4800RK, the Netherlands; 2Erasmus Medical Centre Rotterdam, Department of Pulmonary Medicine, Rotterdam, 3015 CE, the Netherlands; 3Erasmuc Medical Centre Rotterdam, Department of Biostatistics, Rotterdam, 3015 CE, the NetherlandsCorrespondence: Sander Talman Tel [phone]Email [e-mail]: Macrolides are effective in reducing the number of exacerbations in COPD patients with the frequent exacerbator phenotype. Our study did not show a persistent effect of azithromycin on exacerbation frequencies after more than one year of usage.Keywords: Macrolide, long-term, exacerbations, COPD, COLUMBUS