Current Approaches Including Novel Nano/Microtechniques to Reduce Silicone Implant-Induced Contracture with Adverse Immune Responses

Capsular contracture, which is the pathologic development of fibrous capsules around implants, is a major complication of reconstructive and aesthetic breast surgeries. Capsular contracture can cause implant failure with breast hardening, deformity, and severe pain. The exact mechanisms underlying t...

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Main Authors:	Shin Hyuk Kang, Chanutchamon Sutthiwanjampa, Chan Yeong Heo, Woo Seob Kim, Soo-Hong Lee, Hansoo Park
Format:	Article
Language:	English
Published:	MDPI AG 2018-04-01
Series:	International Journal of Molecular Sciences
Subjects:	silicone breast implant capsular contracture foreign body reaction T-cell immunity ALCL nano/microtechniques
Online Access:	http://www.mdpi.com/1422-0067/19/4/1171

id	doaj-adaad7f14ff642b199d47de1df85d5ea
record_format	Article
spelling	doaj-adaad7f14ff642b199d47de1df85d5ea2020-11-25T00:50:09ZengMDPI AGInternational Journal of Molecular Sciences1422-00672018-04-01194117110.3390/ijms19041171ijms19041171Current Approaches Including Novel Nano/Microtechniques to Reduce Silicone Implant-Induced Contracture with Adverse Immune ResponsesShin Hyuk Kang0Chanutchamon Sutthiwanjampa1Chan Yeong Heo2Woo Seob Kim3Soo-Hong Lee4Hansoo Park5Department of Plastic and Reconstructive Surgery, Chung-Ang University Graduate School of Medicine, Seoul 06974, KoreaSchool of Integrative Engineering, Chung-Ang University, Seoul 06974, KoreaDepartment of Plastic and Reconstructive Surgery, Seoul National University College of Medicine, Kyunggi 13620, KoreaDepartment of Plastic and Reconstructive Surgery, Chung-Ang University Graduate School of Medicine, Seoul 06974, KoreaDepartment of Medical Bioscience, CHA University, Kyunggi 13488, KoreaSchool of Integrative Engineering, Chung-Ang University, Seoul 06974, KoreaCapsular contracture, which is the pathologic development of fibrous capsules around implants, is a major complication of reconstructive and aesthetic breast surgeries. Capsular contracture can cause implant failure with breast hardening, deformity, and severe pain. The exact mechanisms underlying this complication remain unclear. In addition, anaplastic large cell lymphoma is now widely recognized as a very rare disease associated with breast implants. Foreign body reactions are an inevitable common denominator of capsular contracture. A number of studies have focused on the associated immune responses and their regulation. The present article provides an overview of the currently available techniques, including novel nano/microtechniques, to reduce silicone implant-induced contracture and associated foreign body responses.http://www.mdpi.com/1422-0067/19/4/1171silicone breast implantcapsular contractureforeign body reactionT-cell immunityALCLnano/microtechniques
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Shin Hyuk Kang Chanutchamon Sutthiwanjampa Chan Yeong Heo Woo Seob Kim Soo-Hong Lee Hansoo Park
spellingShingle	Shin Hyuk Kang Chanutchamon Sutthiwanjampa Chan Yeong Heo Woo Seob Kim Soo-Hong Lee Hansoo Park Current Approaches Including Novel Nano/Microtechniques to Reduce Silicone Implant-Induced Contracture with Adverse Immune Responses International Journal of Molecular Sciences silicone breast implant capsular contracture foreign body reaction T-cell immunity ALCL nano/microtechniques
author_facet	Shin Hyuk Kang Chanutchamon Sutthiwanjampa Chan Yeong Heo Woo Seob Kim Soo-Hong Lee Hansoo Park
author_sort	Shin Hyuk Kang
title	Current Approaches Including Novel Nano/Microtechniques to Reduce Silicone Implant-Induced Contracture with Adverse Immune Responses
title_short	Current Approaches Including Novel Nano/Microtechniques to Reduce Silicone Implant-Induced Contracture with Adverse Immune Responses
title_full	Current Approaches Including Novel Nano/Microtechniques to Reduce Silicone Implant-Induced Contracture with Adverse Immune Responses
title_fullStr	Current Approaches Including Novel Nano/Microtechniques to Reduce Silicone Implant-Induced Contracture with Adverse Immune Responses
title_full_unstemmed	Current Approaches Including Novel Nano/Microtechniques to Reduce Silicone Implant-Induced Contracture with Adverse Immune Responses
title_sort	current approaches including novel nano/microtechniques to reduce silicone implant-induced contracture with adverse immune responses
publisher	MDPI AG
series	International Journal of Molecular Sciences
issn	1422-0067
publishDate	2018-04-01
description	Capsular contracture, which is the pathologic development of fibrous capsules around implants, is a major complication of reconstructive and aesthetic breast surgeries. Capsular contracture can cause implant failure with breast hardening, deformity, and severe pain. The exact mechanisms underlying this complication remain unclear. In addition, anaplastic large cell lymphoma is now widely recognized as a very rare disease associated with breast implants. Foreign body reactions are an inevitable common denominator of capsular contracture. A number of studies have focused on the associated immune responses and their regulation. The present article provides an overview of the currently available techniques, including novel nano/microtechniques, to reduce silicone implant-induced contracture and associated foreign body responses.
topic	silicone breast implant capsular contracture foreign body reaction T-cell immunity ALCL nano/microtechniques
url	http://www.mdpi.com/1422-0067/19/4/1171
work_keys_str_mv	AT shinhyukkang currentapproachesincludingnovelnanomicrotechniquestoreducesiliconeimplantinducedcontracturewithadverseimmuneresponses AT chanutchamonsutthiwanjampa currentapproachesincludingnovelnanomicrotechniquestoreducesiliconeimplantinducedcontracturewithadverseimmuneresponses AT chanyeongheo currentapproachesincludingnovelnanomicrotechniquestoreducesiliconeimplantinducedcontracturewithadverseimmuneresponses AT wooseobkim currentapproachesincludingnovelnanomicrotechniquestoreducesiliconeimplantinducedcontracturewithadverseimmuneresponses AT soohonglee currentapproachesincludingnovelnanomicrotechniquestoreducesiliconeimplantinducedcontracturewithadverseimmuneresponses AT hansoopark currentapproachesincludingnovelnanomicrotechniquestoreducesiliconeimplantinducedcontracturewithadverseimmuneresponses
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Current Approaches Including Novel Nano/Microtechniques to Reduce Silicone Implant-Induced Contracture with Adverse Immune Responses

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