Nanopore extended field-effect transistor for selective single-molecule biosensing

Efficient detection of single molecules is vital to many biosensing technologies, which require analytical platforms with high selectivity and sensitivity. Ren et al. combine a nanopore sensor and a field-effect transistor, whereby gate voltage mediates DNA and protein transport through the nanopore...

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Main Authors:	Ren Ren, Yanjun Zhang, Binoy Paulose Nadappuram, Bernice Akpinar, David Klenerman, Aleksandar P. Ivanov, Joshua B. Edel, Yuri Korchev
Format:	Article
Language:	English
Published:	Nature Publishing Group 2017-09-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-017-00549-w

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spelling	doaj-ada18185ce2e43c6bc7be5e8643604b12021-05-11T07:39:21ZengNature Publishing GroupNature Communications2041-17232017-09-01811910.1038/s41467-017-00549-wNanopore extended field-effect transistor for selective single-molecule biosensingRen Ren0Yanjun Zhang1Binoy Paulose Nadappuram2Bernice Akpinar3David Klenerman4Aleksandar P. Ivanov5Joshua B. Edel6Yuri Korchev7Department of Medicine, Imperial College LondonDepartment of Medicine, Imperial College LondonDepartment of Chemistry, Imperial College LondonDepartment of Chemistry, Imperial College LondonDepartment of Chemistry, University of CambridgeDepartment of Chemistry, Imperial College LondonDepartment of Chemistry, Imperial College LondonDepartment of Medicine, Imperial College LondonEfficient detection of single molecules is vital to many biosensing technologies, which require analytical platforms with high selectivity and sensitivity. Ren et al. combine a nanopore sensor and a field-effect transistor, whereby gate voltage mediates DNA and protein transport through the nanopore.https://doi.org/10.1038/s41467-017-00549-w
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Ren Ren Yanjun Zhang Binoy Paulose Nadappuram Bernice Akpinar David Klenerman Aleksandar P. Ivanov Joshua B. Edel Yuri Korchev
spellingShingle	Ren Ren Yanjun Zhang Binoy Paulose Nadappuram Bernice Akpinar David Klenerman Aleksandar P. Ivanov Joshua B. Edel Yuri Korchev Nanopore extended field-effect transistor for selective single-molecule biosensing Nature Communications
author_facet	Ren Ren Yanjun Zhang Binoy Paulose Nadappuram Bernice Akpinar David Klenerman Aleksandar P. Ivanov Joshua B. Edel Yuri Korchev
author_sort	Ren Ren
title	Nanopore extended field-effect transistor for selective single-molecule biosensing
title_short	Nanopore extended field-effect transistor for selective single-molecule biosensing
title_full	Nanopore extended field-effect transistor for selective single-molecule biosensing
title_fullStr	Nanopore extended field-effect transistor for selective single-molecule biosensing
title_full_unstemmed	Nanopore extended field-effect transistor for selective single-molecule biosensing
title_sort	nanopore extended field-effect transistor for selective single-molecule biosensing
publisher	Nature Publishing Group
series	Nature Communications
issn	2041-1723
publishDate	2017-09-01
description	Efficient detection of single molecules is vital to many biosensing technologies, which require analytical platforms with high selectivity and sensitivity. Ren et al. combine a nanopore sensor and a field-effect transistor, whereby gate voltage mediates DNA and protein transport through the nanopore.
url	https://doi.org/10.1038/s41467-017-00549-w
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Nanopore extended field-effect transistor for selective single-molecule biosensing

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