mmquant: how to count multi-mapping reads?
Abstract Background RNA-Seq is currently used routinely, and it provides accurate information on gene transcription. However, the method cannot accurately estimate duplicated genes expression. Several strategies have been previously used (drop duplicated genes, distribute uniformly the reads, or est...
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| Format: | Article |
| Language: | English |
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BMC
2017-09-01
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| Series: | BMC Bioinformatics |
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| Online Access: | http://link.springer.com/article/10.1186/s12859-017-1816-4 |