Mathematical Model of Dynamic Protein Interactions Regulating p53 Protein Stability for Tumor Suppression

In the field of cancer biology, numerous genes or proteins form extremely complex regulatory network, which determines cancer cell fate and cancer cell survival. p53 is a major tumor suppressor that is lost in more than 50% of human cancers. It has been well known that a variety of proteins regulate...

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Bibliographic Details
Main Authors: Hua Wang, Guang Peng
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Computational and Mathematical Methods in Medicine
Online Access:http://dx.doi.org/10.1155/2013/358980