Acute and chronic administration of cannabidiol increases mitochondrial complex and creatine kinase activity in the rat brain

Acute and chronic administration of cannabidiol increases mitochondrial complex and creatine kinase activity in the rat brain

Objective: To investigate the effects of cannabidiol (CBD) on mitochondrial complex and creatine kinase (CK) activity in the rat brain using spectrophotometry. Method: Male adult Wistar rats were given intraperitoneal injections of vehicle or CBD (15, 30, or 60 mg/kg) in an acute (single dose) or...

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Bibliographic Details
Main Authors: Samira S. Valvassori, Daniela V. Bavaresco, Giselli Scaini, Roger B. Varela, Emilio L. Streck, Marcos H. Chagas, Jaime E.C. Hallak, Antonio W. Zuardi, José A. Crippa, João Quevedo
Format: Article
Language:English
Published: Associação Brasileira de Psiquiatria (ABP) 2013-12-01
Series:Brazilian Journal of Psychiatry
Subjects:
Cannabidiol
mitochondrial respiratory chain
creatine kinase
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462013000400380&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462013000400380&lng=en&tlng=en

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