FTIR Microspectroscopy Coupled with Two-Class Discrimination Segregates Markers Responsible for Inter- and Intra-Category Variance in Exfoliative Cervical Cytology

Infrared (IR) absorbance of cellular biomolecules generates a vibrational spectrum, which can be exploited as a “biochemical fingerprint” of a particular cell type. Biomolecules absorb in the mid-IR (2–20 μm) and Fourier-transform infrared (FTIR) microspectroscopy applied to discriminate different c...

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Bibliographic Details
Main Authors: Michael J. Walsh, Maneesh N. Singh, Helen F. Stringfellow, Hubert M. Pollock, Azzedine Hammiche, Olaug Grude, Nigel J. Fullwood, Mark A. Pitt, Pierre L. Martin-Hirsch, Francis L. Martin
Format: Article
Language:English
Published: SAGE Publishing 2008-01-01
Series:Biomarker Insights
Online Access:https://doi.org/10.4137/BMI.S592