Anti-Tumor Efficacy of PD-L1 Targeted Alpha-Particle Therapy in a Human Melanoma Xenograft Model

Anti-Tumor Efficacy of PD-L1 Targeted Alpha-Particle Therapy in a Human Melanoma Xenograft Model

PD-L1 (programmed death-ligand 1, B7-H1, CD274), the ligand for PD-1 inhibitory receptor, is expressed on various tumors, and its expression is correlated with a poor prognosis in melanoma. Anti-PD-L1 mAbs have been developed along with anti-CTLA-4 and anti-PD-1 antibodies for immune checkpoint inhi...

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Bibliographic Details
Main Authors: Marisa Capitao, Justine Perrin, Sylvain Simon, Sébastien Gouard, Nicolas Chouin, Frank Bruchertseifer, Alfred Morgenstern, Latifa Rbah-Vidal, Michel Chérel, Emmanuel Scotet, Nathalie Labarrière, Yannick Guilloux, Joëlle Gaschet
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Cancers
Subjects:
TAT
PD-L1
melanoma
bismuth-213
theranostics
Online Access:https://www.mdpi.com/2072-6694/13/6/1256

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