Recent advances in screening of enzymes inhibitors based on capillary electrophoresis

Recent advances in screening of enzymes inhibitors based on capillary electrophoresis

Capillary electrophoresis with many advantages plays an important role in pharmaceutical analysis and drug screening. This review gives an overview on the recent advances in the developments and applications of capillary electrophoresis in the field of enzyme inhibitor screening. The period covers 2...

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Main Authors: Mengxia Cheng, Zilin Chen
Format: Article
Language:English
Published: Elsevier 2018-08-01
Series:Journal of Pharmaceutical Analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S2095177918300431
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spelling doaj-ad8333dbc1234852871319148fa2b44a2021-04-02T13:24:25ZengElsevierJournal of Pharmaceutical Analysis2095-17792018-08-0184226233Recent advances in screening of enzymes inhibitors based on capillary electrophoresisMengxia Cheng0Zilin Chen1Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Ministry of Education, and Wuhan University, School of Pharmaceutical Sciences, Wuhan 430071, ChinaCorresponding author.; Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Ministry of Education, and Wuhan University, School of Pharmaceutical Sciences, Wuhan 430071, ChinaCapillary electrophoresis with many advantages plays an important role in pharmaceutical analysis and drug screening. This review gives an overview on the recent advances in the developments and applications of capillary electrophoresis in the field of enzyme inhibitor screening. The period covers 2013 to 2017. Both the pre-capillary enzyme assays and in-capillary enzyme assays which include electrophoretically mediated microanalysis (EMMA) and immobilized enzyme microreactor (IMER) are summarized in this article. Keywords: Capillary electrophoresis, Enzyme inhibitor screening, Pre-capillary enzyme assays, Electrophoretically mediated microanalysis, Immobilized enzyme microreactorhttp://www.sciencedirect.com/science/article/pii/S2095177918300431
collection DOAJ
language English
format Article
sources DOAJ
author Mengxia Cheng
Zilin Chen
spellingShingle Mengxia Cheng
Zilin Chen
Recent advances in screening of enzymes inhibitors based on capillary electrophoresis
Journal of Pharmaceutical Analysis
author_facet Mengxia Cheng
Zilin Chen
author_sort Mengxia Cheng
title Recent advances in screening of enzymes inhibitors based on capillary electrophoresis
title_short Recent advances in screening of enzymes inhibitors based on capillary electrophoresis
title_full Recent advances in screening of enzymes inhibitors based on capillary electrophoresis
title_fullStr Recent advances in screening of enzymes inhibitors based on capillary electrophoresis
title_full_unstemmed Recent advances in screening of enzymes inhibitors based on capillary electrophoresis
title_sort recent advances in screening of enzymes inhibitors based on capillary electrophoresis
publisher Elsevier
series Journal of Pharmaceutical Analysis
issn 2095-1779
publishDate 2018-08-01
description Capillary electrophoresis with many advantages plays an important role in pharmaceutical analysis and drug screening. This review gives an overview on the recent advances in the developments and applications of capillary electrophoresis in the field of enzyme inhibitor screening. The period covers 2013 to 2017. Both the pre-capillary enzyme assays and in-capillary enzyme assays which include electrophoretically mediated microanalysis (EMMA) and immobilized enzyme microreactor (IMER) are summarized in this article. Keywords: Capillary electrophoresis, Enzyme inhibitor screening, Pre-capillary enzyme assays, Electrophoretically mediated microanalysis, Immobilized enzyme microreactor
url http://www.sciencedirect.com/science/article/pii/S2095177918300431
work_keys_str_mv AT mengxiacheng recentadvancesinscreeningofenzymesinhibitorsbasedoncapillaryelectrophoresis
AT zilinchen recentadvancesinscreeningofenzymesinhibitorsbasedoncapillaryelectrophoresis
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