Torpor: The Rise and Fall of 3-Monoiodothyronamine from Brain to Gut—From Gut to Brain?

3-Monoiodothyronamine (T1AM), first isolated from rat brain, is reported to be an endogenous, rapidly acting metabolite of thyroxine. One of its numerous effects is the induction of a “torpor-like” state in experimental animals. A critical analysis of T1AM, to serve as an endogenous cryogen, is give...

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Bibliographic Details
Main Authors: Hartmut H. Glossmann, Oliver M. D. Lutz
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-05-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fendo.2017.00118/full