Modulation of the Hypothalamic Nutrient Sensing Pathways by Sex and Early-Life Stress

Modulation of the Hypothalamic Nutrient Sensing Pathways by Sex and Early-Life Stress

There are sex differences in metabolic disease risk, and early-life stress (ES) increases the risk to develop such diseases, potentially in a sex-specific manner. It remains to be understood, however, how sex and ES affect such metabolic vulnerability. The hypothalamus regulates food intake and ener...

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Bibliographic Details
Main Authors: Silvie R. Ruigrok, Nina Stöberl, Kit-Yi Yam, Chiara de Lucia, Paul J. Lucassen, Sandrine Thuret, Aniko Korosi
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Neuroscience
Subjects:
nutrient sensing
hypothalamus
sex differences
early-life stress
metabolism
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2021.695367/full

Internet

https://www.frontiersin.org/articles/10.3389/fnins.2021.695367/full

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