Effect of endotoxin on cholesterol biosynthesis and distribution in serum lipoproteins in Syrian hamsters.

Effect of endotoxin on cholesterol biosynthesis and distribution in serum lipoproteins in Syrian hamsters.

Infection and inflammation increase serum triglyceride and cholesterol levels in rodents and rabbits. Endotoxin (LPS) has been used as a model of infection and its effects on triglyceride metabolism have been previously characterized. In the present study we demonstrate that both low (100 ng/100 g b...

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Bibliographic Details
Main Authors: Kenneth R. Feingold, Ingibjorg Hardardottir, Riaz Memon, Eveline J.T. Krul, Arthur H. Moser, John M. Taylor, Carl Grunfeld
Format: Article
Language:English
Published: Elsevier 1993-12-01
Series:Journal of Lipid Research
Subjects:
HMG-CoA reductase
LDL receptor
apoE
apoA-I
acute phase response
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520353554

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